✓ Evidence Based

Signs & Symptoms Of Low Testosterone

Low testosterone, also known as hypogonadism (1), affects millions of people worldwide and can have a profound impact on both physical and mental well-being.

That’s why in this article, we will dive deep into the signs and symptoms of low testosterone.

9 Signs & Symptoms Of Low Testosterone

It’s important to note that these symptoms may not necessarily be indicative of low testosterone alone. They can be associated with other medical conditions.

Therefore, consulting with a healthcare professional is crucial for an accurate diagnosis.

1. Consistent Tiredness

When testosterone levels decline below normal ranges, you may experience persistent fatigue and a lack of energy.

Low testosterone can impact both physical and mental aspects of health, leading to feelings of exhaustion and lethargy.

Fatigue caused by low testosterone can be accompanied by other symptoms. These include reduced motivation, decreased libido, difficulty concentrating, and mood changes.

The connection between low testosterone and fatigue can be explained by the hormone’s influence on various bodily functions.

Testosterone helps regulate metabolism, red blood cell production, and the functioning of the cardiovascular system.

When levels are low, these processes may be disrupted. This leads to decreased energy production and circulation, ultimately resulting in persistent tiredness.

2. Trouble with managing weight

Managing weight can be challenging for many people, and various factors can contribute to this difficulty.

One potential factor that is often overlooked is the role of testosterone levels in weight management.

Testosterone, a crucial hormone predominantly found in males but also present in females. It plays a vital role in regulating metabolism, muscle mass, and fat distribution.

Research suggests that low testosterone levels can lead to an increase in body fat and a decrease in muscle mass.

This imbalance can result in a slower metabolic rate, making it harder to burn calories effectively and maintain a healthy weight.

Moreover, low testosterone levels can also contribute to a decrease in energy levels and motivation. This makes it challenging to engage in regular exercise and physical activity.

Low testosterone levels can also disrupt the body’s ability to regulate insulin, leading to insulin resistance (2).

This condition can cause fluctuations in blood sugar levels and promote the storage of excess fat, particularly in the abdominal area.

Additionally, low testosterone levels may affect appetite regulation and increase cravings for unhealthy, high-calorie foods, further complicating weight management efforts.

It is important to note that while low testosterone levels can be a contributing factor to weight management issues, they are not the sole determinant.

Various other factors, including diet, lifestyle, genetics, and overall health, also play crucial roles in weight management.

3. Mood changes

Low testosterone levels can lead to a range of mood changes in men.

Studies have shown that decreased testosterone levels are associated with an increased risk of developing symptoms of depression, irritability, and mood swings.

Additionally, individuals with low testosterone may experience fatigue, decreased motivation, and a reduced sense of well-being, further contributing to changes in mood.

The hormonal imbalance caused by low testosterone can disrupt the delicate neurotransmitter balance (3) in the brain, leading to emotional instability.

Testosterone plays a vital role in regulating serotonin (4), dopamine, and other neurotransmitters that impact mood regulation.

When testosterone levels are insufficient, this delicate balance can be disturbed, leading to mood disturbances and increased stress.

4. Low libido

Low libido (5) can be indicative of various underlying factors.

One potential cause that has garnered significant attention is low testosterone levels.

While low testosterone is not the sole reason behind decreased libido, it is considered a possible contributing factor.

Testosterone impacts the desire to get active in the bedroom by stimulating the brain’s receptors responsible for sensual thoughts and fantasies.

In people with low testosterone levels, this process may be disrupted, leading to a diminished interest in spicing things up with your partner.

Other symptoms of low testosterone, such as fatigue, mood swings, and reduced muscle mass, can further contribute to decreased libido.

However, it is essential to note that low libido can arise from a multitude of causes, including psychological factors, relationship issues, medication side effects, and certain health conditions.

Therefore, it is crucial to consult with a healthcare professional for an accurate diagnosis and appropriate treatment.

5. Trouble sleeping

Trouble sleeping is often overlooked as a potential sign of low testosterone levels in individuals.

While it is commonly known for its impact on libido and muscle development, testosterone also influences sleep patterns and overall well-being.

Research suggests that low testosterone levels can disrupt the delicate balance of the body’s sleep-wake cycle.

This hormone helps regulate sleep by influencing the production of melatonin, a hormone responsible for inducing sleepiness.

When testosterone levels are low, it can lead to disturbances in melatonin (6) production, resulting in difficulties falling asleep and maintaining a restful sleep throughout the night.

Furthermore, low testosterone levels can contribute to other sleep-related issues.

People with low testosterone may experience increased daytime fatigue, daytime sleepiness, and a general lack of energy.

These symptoms can further impact their ability to function optimally during the day and may lead to decreased productivity and overall quality of life.

6. Hair loss

Hair loss is a common concern that affects millions of men worldwide, and it can be attributed to various factors.

While genetics, aging, and certain medical conditions are often associated with hair loss, there is a widely held belief that low testosterone levels can also contribute to this condition.

However, it is important to note that the relationship between hair loss and testosterone levels is more complex than a simple cause-and-effect scenario.

While testosterone is involved in the regulation of hair growth, the role it plays in male pattern baldness is not fully understood.

It is believed that an enzyme called 5-alpha-reductase converts testosterone into a more potent form called dihydrotestosterone, which can affect hair follicles and lead to their miniaturization.

While low testosterone levels can potentially contribute to hair loss, it is not the sole determining factor.

Genetic predisposition and sensitivity to dihydrotestosterone (7), along with other hormonal and environmental factors, also play significant roles in the development of hair loss.

7. Pessimistic and obsessive thoughts

Research suggests that testosterone has an impact on neurotransmitters, such as serotonin and dopamine, which are closely tied to mood and cognition.

When testosterone levels are low, individuals may experience a variety of psychological symptoms, including pessimistic and obsessive thoughts.

Low testosterone can potentially disrupt the delicate balance of neurotransmitters, leading to altered mood states and negative thinking patterns.

Furthermore, low testosterone has been associated with increased irritability, reduced motivation, and decreased concentration, all of which can contribute to a pessimistic mindset.

However, it’s important to note that pessimistic and obsessive thoughts can arise from various causes, including psychological factors and other medical conditions.

8. Weakened memory

Memory loss and cognitive decline can be concerning symptoms, affecting individuals in various aspects of their lives.

While several factors can contribute to weakened memory, including aging, stress, and certain medical conditions, one lesser-known but significant contributor is low testosterone levels in men.

Studies have revealed a strong correlation between low testosterone and cognitive decline, particularly in memory-related tasks.

Testosterone receptors are present in key brain regions responsible for memory formation and retrieval, such as the hippocampus (8).

When testosterone levels decrease, these receptors may be affected, impacting cognitive processes.

Low testosterone has also been linked to conditions such as hypogonadism, which is a condition characterized by reduced or absent testosterone production.

Hypogonadism can affect both younger and older men and is associated with symptoms like fatigue, depression, and memory impairment.

9. Loss of muscle mass

Testosterone is responsible for stimulating protein synthesis (9) within muscle cells, which promotes muscle growth and repair.

It also aids in the regulation of muscle size and strength by enhancing muscle fiber size and increasing muscle contractile proteins.

Consequently, lower testosterone levels can result in a decrease in muscle protein synthesis and an overall reduction in muscle mass.

In addition, testosterone plays a vital role in preventing the breakdown of muscle tissue.

It acts as an anti-catabolic hormone (10), inhibiting the activity of certain enzymes that break down muscle proteins.

When testosterone levels are low, this protective effect diminishes, leading to an increased breakdown of muscle tissue.

Low testosterone can also lead to an imbalance between muscle and fat tissue.

Testosterone helps regulate fat metabolism by promoting the use of stored fat as an energy source.

When testosterone levels decline, the body may experience an increase in fat accumulation and a decrease in muscle mass.

Causes of low testosterone

Several factors can contribute to low testosterone levels in both men and women.

One of the primary causes is age. As individuals grow older, the production of testosterone naturally declines.

Certain medical conditions can also contribute to low testosterone.

Hypogonadism can occur as a result of dysfunction or damage to the testes or ovaries, such as testicular or ovarian cancer, infections, or trauma.

Additionally, hormonal disorders like pituitary gland abnormalities, thyroid dysfunction, or certain autoimmune diseases can disrupt the hormonal balance and lead to reduced testosterone production.

Lifestyle factors can also play a role in testosterone levels.

Chronic stress, lack of quality sleep, excessive alcohol consumption, smoking, and obesity have been associated with lower testosterone levels.


It is essential to recognize the potential causes of low testosterone as early detection and treatment can significantly improve an individual’s quality of life.

While aging is a common cause of declining testosterone levels, other factors such as certain medical conditions, obesity, and medications can also contribute to low testosterone.

Treatment options for low testosterone may involve hormone replacement therapy or addressing the underlying cause.

It is always recommended to consult with a healthcare professional for an accurate diagnosis and appropriate management of low testosterone.